Pathophysiology lesson: nephrotic syndrome

Nephrotic syndrome is a group of symptoms that occur with some kidney diseases, such as FSGS, minimal change disease, and glomerulonephritis. 

Symptoms include: frothy urine, low blood albumin levels, high urine protein levels, high cholesterol levels, edema

Nephrotic syndrome occurs when the glomerli of the kidneys are damaged. The glomerli are a sack of blood vessels that clean impurities out of the blood. They are located within the nephrons.

Risk factors include: certain infections, certain kidney diseases, a disease that can lead to kidney damage, and using certain pain killers such as motrin.

Complications include: blood clots, malnutrition, acute kidney failure, chronic kidney failure. Blood clots form because of the lack of albumin in the blood. For this reason most people take aspirin.

Treatment includes: diuretics (to get rid of edema), blood pressure pills (for high blood pressure and some aid in lowering proteinuria as well as edema), cholesterol reducing medications, blood thinners, and immunosuppressants. It is not well understood how immunosuppressants help the kidney.

citation: my life (:p) and http://www.mayoclinic.com/health/nephrotic-syndrome/DS01047/DSECTION=treatments%2Dand%2Ddrugs

nephrotic syndrome fsgs ckd kidney disease

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